Skip to main content
AAO-HNSF 2025 Annual Meeting & OTO EXPO Main banner
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Rate ePoster
Video

Rhinology/Allergy

(A1124) Inverted papilloma from the Maxillary sinus: Recurrences after more than 5 years of follow-up

Monday, October 13, 2025
12:00 PM - 1:00 PM EDT
Location: OTO EXPO, Posters

    Presenting Author(s)

  • Jae Hyuk Choi, MD

    2nd year resident
    Pusan National University Yangsan Hospital
    Busan, Pusan-jikhalsi, Republic of Korea

    • Senior Author(s)

  • Sue Jean Mun, MD, PhD

    Associate professor
    Pusan National University Yangsan Hospital
    Yangsan, Republic of Korea

Disclosure(s):
Sue Jean Mun, MD, PhD: No relevant relationships to disclose.
Jae Hyuk Choi, MD: No relevant relationships to disclose.


Introduction: Inverted papilloma (IP) is a sinonasal benign tumor with a high local invasiveness, the potential to progress to cancer, and a very high recurrence rate. Surgical techniques have developed to approach the origin site of the maxillary sinus (MS) besides endoscopic sinus surgery (ESS): the Caldwell-Luc approach (CLA) and the endoscopic modified medial maxillectomy (EMMM) techniques such as prelacrimal recess approach or inferior turbinate swing technique. In this study, we aimed to analyze the prognosis of various surgical approaches of MS IPs.

Methods: A retrospective cross-sectional study was conducted in patients who were diagnosed as MS IPs from 2003 to 2023. Age at diagnosis, sex, hyperostosis on the computed tomography, operation records, the recurrence and the malignant transformation were evaluated. Excluding 2 cases of total maxillectomy, subgroup analysis on recurrence rate was performed according to surgical techniques.

Results: Among 59 cases (44 male, mean 58.9 years), 11.9% were revision cases. Hyperostosis was found in 49.2%, most frequently in superior wall (SW) followed by anterior (AW) and posterior walls. AW (44.1%) was found to be the most prevalent origin followed by superior (35.6%), and medial wall (MW, 33.9%). More than half (52.5%) originated from more than two walls of the MS. The overall recurrence rate was 16.9% after a mean follow-up period of 60.0 months. Malignant transformation was found in 13.6% (6 synchronous and 2 metachronous). The recurrence rate was 29.2% after ESS (n=24), 12.8% after CLA (n=19), 0% after EMMM (n=14). EMMM showed less recurrence compared to ESS (p=0.033). Time until the recurrence was 47.5 months after ESS and 105.0 months after CLA (p=0.033). Especially there were 3 cases of AW recurrence after CLA after 10 years of the first operation.

Conclusions: AW of MS might be a blind spot for CLA. Long-term follow-up more than 10 years might be needed after CLA.