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Video

Rhinology/Allergy

(A1132) Proptosis in Rhino-Orbital Mucormycosis: Associated CT scan findings

Monday, October 13, 2025
12:00 PM - 1:00 PM EDT
Location: OTO EXPO, Posters

    Senior Author(s)

  • Mohsen Naraghi, MD, FARS

    Triple Board Certified Rhinologist and Facial Plastic Reconstructive Surgeon
    Orphans Worldwide
    Jacksonville, Florida, United States

    • Presenting Author(s)

  • Hamed Sarikhani, MD

    assistant professor
    Montefiore Medical Center
    New Rochelle, New York, United States

Disclosure(s):
Mohsen Naraghi, MD, FARS: No relevant relationships to disclose.
Hamed Sarikhani, MD: No relevant relationships to disclose.


Introduction: Mucormycosis can lead to severe proptosis, threatening both the visual function and overall prognosis of the patients when it involves the orbital region. Understanding the underlying mechanisms of proptosis in patients with mucormycosis is of paramount importance, as timely recognition and intervention are critical. Computerized tomography (CT) scan has been used as the first radiological imaging device for assessing the extent of the disease, in which images were evaluated for bone erosion, sinus opacification, and proptosis of the eye. This study focuses on the CT scan findings in patients with rhinologic involvement of the mucormycosis infection and its relation to proptosis.

Methods: This study is a cross-sectional study of patients infected with mucormycosis without previous surgical intervention who were referred to a tertiary otolaryngology hospital from October 2020 to October 2021. The inclusion criteria were age more than 18 years old, symptoms of sinusitis, and confirmation of mucormycosis in specimens from sinus surgery based on pathologic assessment. Patients infected with mucormycosis but not of rhino-orbital origin and patients with previous sinus surgery were excluded from the study.

Results: Of 89 included patients, 47 (52.8%) were male and 42 (47.2%) female, with an average age of 56.25±12.42 years. The most common radiologic finding was opacification of the maxillary sinus (87.6%), followed by the ethmoid sinus (84.3%) and the sphenoid sinus (69.7%). Proptosis was reported in 21 patients (23.60%). There was a statistically significantly higher rate of opacification of the ethmoid sinus in patients with proptosis (100.0% versus 79.4%, p-value=0.016).

Conclusions: In conclusion, proptosis is a remarkable ocular manifestation of mucormycosis that warrants urgent attention. This article showed a higher rate of opacification of the ethmoid sinus in patients with proptosis. By increasing awareness and knowledge in this area, we hope to contribute to improved outcomes, reduced morbidity, and enhanced quality of life for those affected by this devastating condition.