(A647) Transoral Robotic Resection of Glossopharyngeal Neurofibroma: A Case Report and Review of the Literature

Introduction: Neurofibromas are benign tumors originating from the peripheral nerve sheath. Solitary oropharyngeal neurofibromas are rarely cited in the literature, and none have been reported with the use of transoral robotic surgery (TORS) for excision. This case highlights the diagnostic challenges posed by oropharyngeal neurofibromas, their potential to mimic other conditions, and the novel application of TORS for management.

Methods: Case study of a solitary neurofibroma masquerading as tonsillitis.

Results: A 47-year-old female presented with a one-year history of a left tonsillar mass. Clinical evaluation, imaging, and biopsy results were inconclusive but raised suspicion for a neoplasm. The patient underwent robotic-assisted tonsillectomy and excision of the mass. Subsequent histopathological evaluation confirmed a benign spindle cell tumor consistent with neurofibroma originating from the glossopharyngeal nerve. The patient recovered postoperatively without any complications.

Conclusions: Oropharyngeal neurofibromas are rare and may present diagnostic challenges due to their resemblance to common tonsillar pathologies. Imaging and biopsies may not always provide definitive diagnoses, necessitating surgical excision for accurate characterization. This case demonstrates the utility of TORS for safe and effective management, offering improved visualization and surgical access while minimizing patient morbidity. Further research is warranted to explore the broader application of TORS in managing head and neck neurofibromas.