(A250) Unique Clinical Presentations of Mucocutaneous Leishmaniasis in the Upperway: Growth Disease in North America

Introduction: Mucocutaneous Leishmaniasis affects more than 90% of tropical countries globally; however, factors such as the displacement of people to tropical areas for work or vacation, deforestation, climate changes, moves, etc. cause the appearance of increasingly frequent cases in North America. It is typically characterized by non-painful ulcers on exposed skin and nasal or nasopharyngeal involvement, although various personal factors can vary its clinical presentation.

Methods: We have managed to compile a collection of atypical clinical lesions of Leishmaniasis in patients treated in the last 25 years of clinical practice in several reference hospitals, which show variants and sequelae of forms of clinical presentation in the upper airway. It can be useful to keep them in mind as a differential diagnosis, since they can be easily confused and generate errors in diagnosis and treatment.

Results: We present a wide collection of atypical cases that affect the nose, oral cavity, and pharynx and explain their clinical picture and differential diagnoses; We also provide several “TIPS” to take into account for correct diagnosis and treatment.

Conclusions: The present collection and the suggested clinical approach will allow the otorhinolaryngologist to correctly diagnose the disease. We also share guidelines for the prevention and early management of this infectious disease.