Navigating Sphenoid Sinus Lesions: Balancing Decision Factors and Treatment Approaches

Sunday, October 12, 2025

4:00 PM - 5:00 PM EDT

Location: 125

Disclosure(s):

Mohamad R. Chaaban, MD, MSCR, MBA:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Stella E. Lee, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Brent A. Senior, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Mahdi A. Shkoukani, MD:

faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

PROGRAM DESCRIPTION: The diagnosis and management of sphenoid sinus lesions are currently a subject of controversy. Unlike the frontal, ethmoid, and maxillary sinuses, sphenoid sinus disease often presents with either no symptoms or intermittent, non-specific symptoms, occasionally leading to vertex headaches.

At present, there is a lack of established diagnostic and treatment algorithms for sphenoid sinus lesions. This session will place a particular emphasis on the diagnosis and management of benign lesions in both asymptomatic and symptomatic patients. The panel will engage in discussions regarding the management of asymptomatic lesions, such as fungus balls in the sphenoid, in both young and older patients, and explore the decision-making process between monitoring and surgical intervention.

Additionally, the panel will delve into surgical approaches for various pathologies, including fungal sinusitis, inverted papillomas, fibro-osseous lesions, and other benign/malignant conditions. The discussions will also extend to addressing CSF leaks located in the sphenoid sinus.

OUTCOME OBJECTIVE 1: Participants will be able to recognize the various clinical presentations, signs and symptoms of sphenoid sinus lesions.

OUTCOME OBJECTIVE 2: Participants will be able to formulate a differential diagnosis of sphenoid sinus lesions.

OUTCOME OBJECTIVE 3: Participants will gain the ability to identify potential options for the medical and surgical management of sphenoid sinus lesions, while actively involving patients in shared decision-making.

BACKGROUND STATEMENT: This topic garnered outstanding feedback, with most faculty recommending it as essential. With no established diagnostic or treatment algorithms, this session will focus on managing benign lesions in asymptomatic and symptomatic patients.

Comprehensive Otolaryngology Track Statement :

Moderator(s)

MC

Mohamad R. Chaaban, MD, MSCR, MBA

Associate Professor
Cleveland Clinic
Cleveland, OH, United States

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.

Panelist(s)

MC

Mohamad R. Chaaban, MD, MSCR, MBA

Associate Professor
Cleveland Clinic
Cleveland, OH, United States

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.
Stella E. Lee, MD

Section Chief—Rhinology
Harvard
Weston, MA, United States

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.
Brent A. Senior, MD

Harold C. Pillsbury, III Distinguished Professor
University of North Carolina
Chapel Hill, NC, United States

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.
Mahdi A. Shkoukani, MD

Department Chair
Cleveland Clinic Abu Dhabi
Troy, MI, United States

Disclosure(s):
faculty for this accredited education activity has no relationship(s) with ineligible companies to disclose.