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Video

Head and Neck Surgery

(A508) Analysis of Alcohol Use Disorder in the Management and Outcomes of Laryngeal Malignancy

Monday, October 13, 2025
12:00 PM - 1:00 PM EDT
Location: OTO EXPO, Posters

    Presenting Author(s)

  • Kaiwen Chen, BS

    Clinical Research Fellow
    Medical University of South Carolina
    Charleston, South Carolina, United States

    • Co-Author(s)

  • Lucy Revercomb, BS

    Medical Student
    Rutgers New Jersey Medical School
    Newark, New Jersey, United States

  • Aman M. Patel, MD

    Resident Physician
    Rutgers New Jersey Medical School
    Newark, New Jersey, United States

  • Anthony M. Saad, BA

    Medical Student
    Rutgers New Jersey Medical School
    Newark, New Jersey, United States

  • Ghayoour S. Mir, DO

    Assistant Professor
    Rutgers New Jersey Medical School
    Newark, NJ, United States

    • Senior Author(s)

  • AF

    Andrey Filimonov, MD, PharmD

    Assistant Professor
    Rutgers New Jersey Medical School
    Newark, New Jersey, United States

Disclosure(s):
Kaiwen Chen, BS: No relevant relationships to disclose.
Lucy Revercomb, BS: No relevant relationships to disclose.
Aman M. Patel, MD: No relevant relationships to disclose.
Anthony M. Saad, BA: No relevant relationships to disclose.
Andrey Filimonov, MD, PharmD: No relevant relationships to disclose.


Introduction: Our study investigates the role of alcohol use disorder (AUD) in the management and outcomes of laryngeal malignancy (LM).

Methods: The 2017 National Inpatient Sample was queried to identify adults with a primary diagnosis of LM (ICD-10: C32). AUD was identified (ICD-10: F10.0-10.9, G62.1, I42.6, K29.2, K70.0-70.4, K70.9, O99.31). Univariate and multivariate analyses were performed to identify statistical associations by AUD status.

Results: Of the 6,825 inpatients identified, the majority were male (78.3%), White (69.2%), and did not have AUD (87.3%). AUD patients had higher incidence of chronic pulmonary disease (50.9% vs. 42.4%), nicotine dependence (65.3% vs. 32.6%), pre-procedure weight loss (50.9% vs. 31.4%), aphagia (41.6% vs. 32.4%), fluid and electrolyte disorders (54.3% vs. 27.3%), deficiency anemias (25.4% vs. 16.4%), and liver disease (7.5% vs. 2.9%) than non-AUD patients (p < 0.001). On multivariable analyses, adjusting for patient and hospital characteristics and metastasis, AUD patients had greater length of stay (12.0 vs. 9.4 days), number of procedures undergone (5.7 vs. 5.3 procedures), and odds for mortality (OR 1.74, 95% CI 1.10–2.74), respiratory failure (OR 1.43, 95% CI 1.19–1.72), and tracheostomy (OR 1.75, 95% CI 1.20–2.56) than non-AUD patients (p < 0.05). AA and non-AUD patients had similar total charges ($130,846 vs. $115,297) and odds for sepsis (OR 1.44, 95% CI 0.98–2.13), urinary tract infection (OR 1.40, 95% CI 0.85–2.30), skin and subcutaneous tissue infections (OR 1.39, 95% 0.94–2.07), and pneumonia (OR 0.92, 95% CI 0.70–1.21) (p>0.05).

Conclusions: In a national cohort of LM inpatients, healthcare utilization and odds for several complications and procedures varied by AUD status.