(A727) Oral Ulceration as a Manifestation of Systemic Tuberculosis

Introduction: Tuberculosis (TB) is a chronic infectious disease primarily affecting the lungs but can also involve other organs, including the oral cavity. Oral TB lesions are rare and can mimic other conditions, posing diagnostic challenges.

Methods: This case report presents a 34-year-old male who visited the Otorhinolaryngology (ORL) department at CEMA Hospital, São Paulo, with a painful ulcerative lesion on the ventral surface of the tongue. Clinical examination, infectious and rheumatological tests, and a biopsy confirmed TB. Imaging revealed lung abnormalities. The patient received a 6-month treatment regimen.

Results: After 15 days of treatment, the patient showed clinical improvement and was considered non-infectious. The lesion on the tongue resolved, and lung imaging improved. Oral TB lesions, though uncommon, can be successfully treated with early diagnosis and appropriate therapy.

Conclusions: Oral tuberculosis is a rare manifestation, often presenting diagnostic challenges. This case highlights the importance of early diagnosis and appropriate multi-drug treatment. Emerging molecular techniques may further improve diagnostic accuracy, aiding in timely intervention.