(A618) Review of Emerging Treatments for Benign Salivary Gland Disease

Introduction: Benign salivary gland diseases, encompassing obstructive, inflammatory, neoplastic, and autoimmune conditions, significantly impact quality of life yet often face limitations in traditional management. This review explores emerging treatments, including minimally invasive techniques, regenerative medicine, and targeted therapies, highlighting their potential to address current challenges and improve patient outcomes.

Methods: This 2024 literature review focused on benign salivary gland disease, examining patients managed by ENT specialists in clinical and surgical settings. Interventions included botox injections, immunotherapies, radiofrequency ablation, and endoscopic surgery. Outcomes highlighted the potential effectiveness of diverse treatments such as gland stimulants, immune-modulating therapies, sialendoscopy, lithotripsy, cryoablation, robotic surgery, transoral approaches, tissue engineering, and gene therapy.

Results: The main outcomes of the study were geared to look at innovative approaches ENT physicians around the world are approaching benign salivary gland disease treatments. There seems to be some very interesting research in many facets of care for these patients that could significantly improve patient outcomes. This paper displays the efficacy of these techniques and therapies. Most of these treatments described above have shown promising datas in the treatment of benign salivary gland disease.

Conclusions: While many of these treatments have shown promise, barriers such as cost, accessibility, and the need for long-term efficacy data persist. This review identifies current knowledge gaps and advocates for collaborative research efforts to optimize the implementation of these emerging therapies. By integrating technological innovations and patient-centered approaches, the future of benign salivary gland disease management holds significant potential for improving outcomes and quality of life.