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Video

Sleep Medicine

(A1200) A Comparative Meta-Analysis of Complications: Maxillomandibular Advancement for OSA versus Orthognathic Surgeries for Dentofacial Deformities

Monday, October 13, 2025
12:00 PM - 1:00 PM EDT
Location: OTO EXPO, Posters

    Presenting Author(s)

  • Mohamed Faisal Kassir, BS

    MD-PhD Student
    Medical University of South Carolina
    Charleston, South Carolina, United States

    • Co-Author(s)

  • Angelica M. Walker, BS

    Medical Student
    Medical University of South Carolina
    Charleston, SC, United States

  • Lauren A. Howser, MD

    Resident Physician
    Medical University of South Carolina
    Charleston, South Carolina, United States

  • SN

    Shaun A. Nguyen, MD

    Professor and Director of Clinical Research
    Medical Univ of South Carolina Dept of OTO
    CHarleston, SC, United States

    • Senior Author(s)

  • Mohamed A. Abdelwahab, MD

    Sleep and Facial Skeletal Surgery, Director
    Medical University of South Carolina
    Charleston, SC, United States

Disclosure(s):
Mohamed Faisal Kassir, BS: No relevant relationships to disclose.
Angelica Walker, BS: No relevant relationships to disclose.
Lauren A. Howser, MD: No relevant relationships to disclose.
Shaun A. Nguyen, MD: No relevant relationships to disclose.


Introduction: Maxillomandibular advancement (MMA) surgeries for obstructive sleep apnea (OSA) and orthognathic surgeries for dentofacial deformities (DFDs) are both complex procedures with distinct indications. This meta-analysis and systematic review aimed to compare surgical outcomes, complications, and recovery metrics between these surgeries.

Methods: A comprehensive search identified studies exclusively discussing MMA surgeries for OSA or orthognathic surgeries for DFDs. A total of 18 studies on bimaxillary orthognathic surgeries (n=1734), 10 on single-jaw surgeries (n=3847), and 17 on MMA surgeries (n=601) were included. Outcomes such as operative duration, length of hospital stay, and complications (e.g., neurosensory disturbance, infections, hardware removal) were analyzed.

Results: Mean surgical success rate of MMA surgeries was 79.6%, while cure rate was 39%. MMA surgeries were associated with a significantly longer operative time (343.87 vs. 326.95 min; p=0.021) and postoperative hospital stay (4.22 vs. 3.25 days; p< 0.05) compared to bimaxillary surgeries. Neurosensory disturbance was comparable between MMA (40.44%) and bimaxillary surgeries (44.91%; p=0.2189), while single-jaw surgeries had the highest rates (55.18%; p< 0.001). Postoperative infection rates were significantly higher in MMA (16.34%) than bimaxillary (3.55%) and single-jaw surgeries (2.15%; p< 0.0001). Hardware removal rates were also greater for MMA (p < 0.0001). Notably, OSA developed postoperatively in 12.25% of individuals undergoing bimaxillary surgery for DFDs.

Conclusions: Our findings underscore the need for tailored preoperative counseling and highlight the importance of risk stratification when selecting orthognathic surgical interventions. This study also highlights the need for a unified and categorical framework to define and report complications accurately. Establishing standardized criteria would enhance the comparability and reliability of future research findings. Future research should focus on optimizing surgical protocols and mitigating postoperative risks in both populations.